Endocrine Abstracts

A 25 year old gentleman was referred to the endocrine clinic for evaluation of abnormal thyroid function tests. He reported symptoms of diffuse abdominal pain associated with loose stool up to six times a day with urgency, frequency and tenesmus. These symptoms had been present since childhood, becoming increasingly troublesome over the preceding two years. He also reported symptoms of tiredness, palpitations and sweating episodes. Thyroid function tests were abnormal. TSH was...

Introduction: Hypothyroidism can present in a variety of ways, from unexpected abnormal blood results in seemingly asymptomatic patients to those with a multitude of debilitating symptoms. Levothyroxine dose titration is a challenge often faced by physicians. We identified 8 difficult cases which following MDT discussion underwent the Thyroxine Absorption Test (TAT) to gain further clarification (Walker et al. 2013).Aim: To identify if the issue...

The prevalence of adrenal incidentaloma on abdominal Computed Tomography (CT) is around 4.4%. This prevalence is increased in obese, diabetic, hypertensive patients, and could be as high as 10% in older patients. Unilateral adrenal masses larger than 4 cm should be considered for surgical removal to avoid missing adrenal carcinoma, particularly in younger patients.This is the case of a 67 year old gentleman with Type 2 diabetes mellitus, known to have hy...

Diabetic nephropathy is the leading cause of chronic kidney disease and is responsible for 30–40% of all end stage renal disease (1). Where there is rapid decline in eGFR, we should also consider other aetiologies.This is the case of a 65-year-old Caucasian gentleman with complex presentation and novel management strategy with type 2 diabetes mellitus since 1999 which was effectively managed, evident by reasonable control of HBA1c; Pharmacotherapy r...

Thyroid cancer is the most common endocrine malignancy with an increasing incidence globally predominantly due to the papillary thyroid carcinoma subtype. It is the 17th and 20th most common malignancy in females and males respectively. In 2018, Cancer Research UK reported 3865 new cases and 400 deaths. Mortality rates are predicted to continue to rise in the UK with an estimated rate of 1 per 100,000 deaths in 2035. We present a 42-year-old female who pr...